Healthy Populations Exam 3 Practice

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Which of the following is a pneumococcal vaccine contraindication?

Allergy to peanuts

Active varicella infection

Age over 65

Any allergies to the pneumococcal vaccine or DTaP/Tdap vaccine

Vaccination safety hinges on true contraindications, which are severe allergic reactions to a vaccine or to a component shared by vaccines. The pneumococcal vaccine (especially the conjugate type) uses a carrier protein derived from diphtheria toxin, so a history of a severe allergy to diphtheria-containing vaccines (DTaP/Tdap) can make giving the pneumococcal vaccine dangerous. That’s why a history of any allergy to the pneumococcal vaccine or to DTaP/Tdap is a valid contraindication.

Allergy to peanuts isn’t related to the vaccine components, so it’s not a contraindication. An active varicella infection represents an acute illness that warrants postponing vaccination, not a true contraindication. Age over 65 isn’t a contraindication—it’s an indication for pneumococcal vaccination in many guidelines.

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