Which screening tool is commonly preferred for high-risk women due to higher sensitivity?

• A. Mammography
• B. Ultrasound
• C. CT scan
• D. MRI

Answer: (D)

Screening effectiveness hinges on sensitivity—the ability to detect cancer when it’s present. For high-risk women, MRI offers the highest sensitivity among common imaging options. The contrast-enhanced MRI highlights tumors by showing abnormal vascularity, making it more likely to detect cancers that mammography or ultrasound may miss, especially in dense breast tissue or in younger women.

Mammography remains important but is less sensitive in dense breasts, which is common in high-risk groups. Ultrasound is a useful adjunct and can help characterize findings, but it isn’t as sensitive overall as MRI for screening purposes. CT is not used for routine breast cancer screening due to radiation exposure and limited utility for detecting breast cancers.